Through Wine possibly, or on a VM, but in that case you're better off just using Windows. Since MNC uses the Unreal Engine 3, you have to see if UE3 can use OpenGL to render. But since Steam is also going to be a requirement, and there's currently no Steam on Linux then I thing you're out of luck.
I have did a little search but don't know if it's real : "2) Some commercial games, especially those based on id software (Doom/Quake) and Epic (Unreal) engines, have native Linux binaries available for download and are virtually identical to their Windows counterparts. Also Neverwinter Nights 1." Maybe there's hope, but I think I will it keep windows. :roll: I guess I would get really bad performance instead of better.
Epic never released the Linux version of their Unreal engine 3 they promised when they launched UT3 (and lots of Linux nerds hate them for that, UT2004 had a Linux version and quite a few people bought Unreal 3 at release to support them thinking they'd release a Linux version at some point), they just released the server for Linux, so you'll most likely never have MNC client run natively. Now you can try with Wine, the windows emulation layer, basically it's Windows' dlls rewritten for Linux, but as far as I know Unreal Engine doesn't go too well with it.
