Every once in a while as Gunner my guns will spin up but nothing comes out. It's like I'm alt-firing but I'm pressing the primary fire button. I'd be tempted to blame the mouse (since it's like 6 years old) but I don't see how that could be the case if the weapon is actually spinning: that should mean the game is recognizing the signal. Has anyone else experienced this?
The mini-gun has a "pre-spin" time when it can't fire. You can reduce this time by running Rate of Fire.
I've had the same thing with the Mortar Launcher. I'll have 2-4 shots left and I'll keep going through the fire animation with no shots coming out until I swap weapons or reload. I keep tossing it up to lag...